Serum vitamin D content is associated with semen parameters and serum testosterone levels in men

The present study aimed to evaluate the influence of serum vitamin D levels on semen quality and testosterone levels. This is a cross-sectional conducted at Androscience, Science Innovation Center in Andrology High-Complex Clinical Laboratory Sao Paulo, Brazil, with 508 male patients, aged 18–60 years, from 2007 2017. Seminal parameters sexual hormones were correlated concentrations 260 men selected by strict selection criteria. Patients divided into normozoospermic group (NZG, n = 124) seminal abnormalities (SAG, 136). Evaluation included complete physical examination, past medical history, habits lifestyle factors, two analysis sperm functional tests, 25-hydroxy-vitamin D3 (25(OH)VD3), total free testosterone, luteinizing hormone (LH), follicle-stimulating (FSH), sex hormone-binding globulin (SHBG), cholesterol, homeostatic model assessment insulin resistance (HOMA-IR) index, karyotype. mean concentration 25(OH)VD3 was significantly lower SAG (P < 0.001) positively all baseline In addition, found be (?= 2.103; P 0.001), number spermatozoa progressive motility (? 2.069; 0.003), motile 2.571; 0.015), morphology 0.056; 0.006), regardless other variables. first comparative address issue content between patients those abnormalities. It clearly demonstrates direct positive relationship level overall quality, reproductive potential,